Vol. 16, No. 2A Framework for Integrating Multiple Biological Networks to Predict MicroRNA-Disease Associations
MicroRNAs have close relationship with human diseases. Therefore, identifying disease related MicroRNAs plays an important role in disease diagnosis, prognosis and therapy. However, designing an effective computational method…
Vol. 16, No. 2HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads
Sequencing of RNA provides the possibility to study an individual’s transcriptome landscape and determine allelic expression ratios. Single-molecule protocols generate multi-kilobase reads longer than most transcripts…
Vol. 16, No. 2OVarCall: Bayesian Mutation Calling Method Utilizing Overlapping Paired-End Reads
Detection of somatic mutations from tumor and matched normal sequencing data has become a standard approach in cancer research.
Vol. 15, No. 8Nanoparticles for siRNA-Based Gene Silencing in Tumor Therapy
Gene silencing through RNA interference (RNAi) has emerged as a potential strategy in manipulating cancer causing genes by complementary base-pairing mechanism. Small interfering RNA (siRNA) is an important RNAi tool that has found significant application in cancer therapy.
Vol. 16, No. 1An End-to-End Model of Plant Pheromone Channel for Long Range Molecular Communication
A new track in molecular communication is using pheromones which can scale up the range of diffusion-based communication from μ meters to meters and enable new applications requiring long range.
Vol. 16, No. 1Performance Evaluation and Optimal Detection of Relay-Assisted Diffusion-Based Molecular Communication With Drift
In this paper, we consider a decode-and-forward (DF) relay-assisted diffusion-based molecular communication system inside one of the blood vessels of a human body with positive drift from transmitter to receiver.