Vol. 16, No. 6 Atomic Force Microscopy in Characterizing Cell Mechanics for Biomedical Applications: A Review
Cell mechanics is a novel label-free biomarker for indicating cell states and pathological changes. The advent of atomic force microscopy (AFM) provides a powerful tool for quantifying the mechanical properties of single living cells in aqueous conditions.
Simultaneous Measurement of Multiple Mechanical Properties of Single Cells Using AFM by Indentation and Vibration
We proposed an indentation-vibration-based method to simultaneously measure the cellular mechanical properties in situ, including cellular mass, elasticity and viscosity, based on the principle of forced vibration stimulated by simple harmonic force using an atomic force microscope system integrated with a piezoelectric transducer as the substrate vibrator.